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6.3 KiB
2 years ago
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["metadata","Designs","Randomized Controlled Trial","Types","BriefSummary","To determine the efficacy, long-term safety, and tolerability of alirocumab , mg every ,\n weeks (Q,W), in comparison with placebo, as well as its potential as a starting regimen. The\n dose regimen of , mg every , weeks (Q,W), as used in other studies, was added as a\n calibrator.","Abstract","To determine the efficacy, long-term safety, and tolerability of alirocumab , mg every ,\n weeks (Q,W), in comparison with placebo, as well as its potential as a starting regimen. The\n dose regimen of , mg every , weeks (Q,W), as used in other studies, was added as a\n calibrator.","Acronym","null","ArticleId","Qy,gwKWSoaWRmbmFEQA","Authors","null","CochraneID","null","Confidential","false","CorporateAuthor","null","Country","Bulgaria, Canada, Hungary, Israel, Norway, Slovakia, United Kingdom, United States","CustomData","null","DatabaseType","ClinicalTrials.gov","DOI","null","EmbaseAccessionNumber","null","Emtree","null","ErrataText","null","FullTextURL","null","Institution","null","ISSN","null","Issue","null","JournalTitle","null","MedlineID","null","MeSH","Hypercholesterolemia|Antibodies, Monoclonal","Pages","null","ParentChildStatus","null","ParentID","null","PublicationDate","March","PublicationYear","PubType","null","ReferenceStudy","null","SecondarySourceID","null","Source","Regeneron Pharmaceuticals","SourceReferenceId","NCT","TaStudyDesign","Randomized","Title","A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab in Patients With Primary Hypercholesterolemia","TrialOutcome","null","Volume","null","Id","Created","VersionNo","ExtractData","null","Digitized","null","IsRapidExtract","false","IsUploaded","false","design","Randomized Controlled Trial","conditions","label","Cholesterol Total Increased","id","SUE_c","phase","name","NCT","trialIds","NCT","acronyms","outcomeCount","id","groups","Id","RefId","B,|O,~Alirocumab , mg Q,W/Up , mg Q,W Without Concomitant Statin","OriginalName","Alirocumab , mg Q,W/Up , mg Q,W Without Concomitant Statin","N","age","ageSD","male","Interventions","termIds","SUBYEL","SUB_Oc","SUNUVb","analyzeAs","Alirocumab","analyzableScore","matchingScore","Id","zB","RefId","B,|O,~Alirocumab , mg Q,W/Up , mg Q,W Without Concomitant Statin","OriginalName","Alirocumab , mg Q,W/Up , mg Q,W Without Concomitant Statin","N","age","ageSD","male","Interventions","termIds","SUBYEL","SUB_Oc","analyzeAs","Statins","analyzableScore","matchingScore","Id","RefId","B,|O,~Placebo Q,W Without Concomitant Statin","OriginalName","Placebo Q,W Without Concomitant Statin","N","age","ageSD","male","Interventions","termIds","SUGeLS","SUBYEL","SUB_Oc","analyzeAs","Control","analyzableScore","matchingScore","Id","tv","RefId","OriginalName","Alirocumab , mg Q,W/Up , mg Q,W","Interventions","termIds","SUCO","SUNUVb","Id","jt","RefId","B,|O,~Alirocumab , mg Q,W/Up , mg Q,W With Concomitant Statin","OriginalName","Alirocumab , mg Q,W/Up , mg Q,W With Concomitant Statin","N","age","ageSD","male","Interventions","termIds","SUBYEL","SUB_Oc","Id","RefId","OriginalName","Alirocumab , mg Q,W/Up , mg Q,W","Interventions","termIds","SUNUVb","Id","RefId","B,|O,~Alirocumab , mg Q,W/Up , mg Q,W With Concomitant Statin","OriginalName","Alirocumab , mg Q,W/Up , mg Q,W With Concomitant Statin","N","age","ageSD","male","Interventions","termIds","SUBYEL","SUB_Oc","SUNUVb","Id","Interventions","Id","Ya","Name","Treatments","Id","((","Phase","k)","Type","Drug","termIds","SUGeLS","SUNUVb","terms","Placebo","Alirocumab","Id","o)","Name","Treatments","Id","Phase","k)","Type","Drug","termIds","SUBYEL","terms","Statins","RefId","E,|Placebo Q,W","OriginalName","Placebo Q,W","Id","Ls","RefId","B,|O,~Placebo Q,W With Concomitant Statin","OriginalName","Placebo Q,W With Concomitant Statin","N","age","ageSD","male","Interventions","termIds","SUGeLS","SUBYEL","SUB_Oc","hasDocData","null","hasRapidExtract","false","N","queryScore","matchingScore","score","outcomes","id","type","Change","unit","%","
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